厌氧菌感染的抗菌治疗要点

Aspects on antibacterial treatment of anaerobic infections.

作者信息

Nordbring F, Nord C E

出版信息

Scand J Infect Dis Suppl. 1982;35:59-62.

Abstract

A review is given of current antibiotic treatment of anaerobic infections. It is emphasized that infections with Bacteroides fragilis constitute the main problem, virtually all other anaerobe organisms of clinical significance are sensitive to penicillin. Particularly useful antibiotics for infections with B. fragilis are cefoxitin, chloramphenicol, clindamycin and the nitroimidazoles. Vancomycin is the drug of choice for pseudomembranous colitis provoked by Clostridium difficile.

摘要

本文综述了目前针对厌氧菌感染的抗生素治疗情况。需强调的是，脆弱拟杆菌感染是主要问题，实际上所有其他具有临床意义的厌氧菌对青霉素敏感。对于脆弱拟杆菌感染特别有效的抗生素有头孢西丁、氯霉素、克林霉素和硝基咪唑类。万古霉素是艰难梭菌引发的伪膜性结肠炎的首选药物。