厌氧菌对FCE 22101的敏感性。
Susceptibility of anaerobic bacteria to FCE 22101.
作者信息
Nord C E, Lindmark A, Person I
出版信息
Antimicrob Agents Chemother. 1987 May;31(5):831-3. doi: 10.1128/AAC.31.5.831.
Abstract
The activity of FCE 22101 against 675 strains of anaerobic bacteria was determined by an agar dilution method. Its activity was compared with those of benzylpenicillin, piperacillin, cefoxitin, imipenem, clindamycin, metronidazole, chloramphenicol, vancomycin, fusidic acid, and bacitracin. FCE 22101 and imipenem (MIC, less than or equal to 0.5 mg/liter) were the most active agents against the anaerobic strains tested, except against Clostridium difficile strains. On the basis of these results, FCE 22101 appears to be a promising antimicrobial agent for treatment of anaerobic infections, and further clinical investigations are indicated.
摘要
采用琼脂稀释法测定了FCE 22101对675株厌氧菌的活性。将其活性与苄青霉素、哌拉西林、头孢西丁、亚胺培南、克林霉素、甲硝唑、氯霉素、万古霉素、夫西地酸和杆菌肽的活性进行了比较。FCE 22101和亚胺培南（MIC≤0.5mg/L）是除艰难梭菌菌株外对所测试厌氧菌最具活性的药物。基于这些结果，FCE 22101似乎是一种有前景的用于治疗厌氧菌感染的抗菌药物，有必要进行进一步的临床研究。
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本文引用的文献
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