左旋咪唑治疗原发性胆汁性肝硬化的临床试验。
A clinical trial of levamisole in primary biliary cirrhosis.
作者信息
Hishon S, Tobin G, Ciclitira P J
出版信息
Postgrad Med J. 1982 Nov;58(685):701-3. doi: 10.1136/pgmj.58.685.701.
Abstract
A small pilot study of levamisole in primary biliary cirrhosis failed to demonstrate any improvement in liver function and immunological abnormalities even in 'early' cases. This may be due to the fact that the defect in the immune system lies in its afferent arm. At present, levamisole, which is potentially toxic, cannot be recommended in conventional doses for the treatment of this disease.
摘要
一项关于左旋咪唑治疗原发性胆汁性肝硬化的小型试点研究表明，即使是“早期”病例，肝功能和免疫异常也未得到任何改善。这可能是由于免疫系统的缺陷在于其传入臂。目前，具有潜在毒性的左旋咪唑不能以常规剂量推荐用于治疗这种疾病。
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