Suppr超能文献

原发性胆汁性肝硬化中植物血凝素(PHA)诱导的淋巴细胞转化及弓形虫抗体研究。细胞介导免疫受损的证据。

Phytohaemagglutinin (PHA) induced lymphocyte transformation and Toxoplasma gondii antibody studies in primary biliary cirrhosis. Evidence of impaired cell-mediated immunity.

作者信息

MacSween R N, Galbraith I, Thomas M A, Watkinson G, Ludlam G B

出版信息

Clin Exp Immunol. 1973 Sep;15(1):35-42.

Abstract

Phytohaemagglutinin (PHA) induced dose-response lymphocyte transformation has been studied in a group of patients with primary biliary cirrhosis. There is a marked reduction in responsiveness, particularly with low doses of PHA. These observations, together with the finding of a raised incidence (7%) of high titre antibody in primary biliary cirrhosis patients, are adduced as evidence of impaired cell-mediated immunity in this disease.

摘要

在一组原发性胆汁性肝硬化患者中研究了植物血凝素(PHA)诱导的剂量反应性淋巴细胞转化。反应性显著降低,尤其是低剂量PHA时。这些观察结果,连同原发性胆汁性肝硬化患者中高滴度抗体发生率升高(7%)的发现,被引为该疾病中细胞介导免疫受损的证据。

引用本文的文献

1
Toxoplasmosis--a global threat. Correlation of latent toxoplasmosis with specific disease burden in a set of 88 countries.
PLoS One. 2014 Mar 24;9(3):e90203. doi: 10.1371/journal.pone.0090203. eCollection 2014.
2
A clinical trial of levamisole in primary biliary cirrhosis.
Postgrad Med J. 1982 Nov;58(685):701-3. doi: 10.1136/pgmj.58.685.701.
3
Serology of primary biliary cirrhosis.
Springer Semin Immunopathol. 1980 Dec;3(3):355-73. doi: 10.1007/BF02054110.
4
Lymphocytotoxic antibodies in primary biliary cirrhosis.
Dig Dis Sci. 1985 Sep;30(9):829-33. doi: 10.1007/BF01309512.
5
Some immunological aspects of liver function.
Yale J Biol Med. 1975 Mar;48(1):47-54.
8
In-vitro reactions of lymphocytes in rheumatoid arthritis and other rheumatic diseases.
Ann Rheum Dis. 1979 Dec;38(6):535-43. doi: 10.1136/ard.38.6.535.

本文引用的文献

1
Dyes as Microchemical Indicators of a New Immunity Phenomenon Affecting a Protozoon Parasite (Toxoplasma).
Science. 1948 Dec 10;108(2815):660-3. doi: 10.1126/science.108.2815.660.
2
[Abdominal symptoms in postnatally acquired toxoplasmosis].
Dtsch Med Wochenschr. 1959 Jul 31;84:1379-84. doi: 10.1055/s-0028-1114454.
4
SEROLOGICAL TESTS IN DIAGNOSIS OF PRIMARY BILIARY CIRRHOSIS.
Lancet. 1965 Apr 17;1(7390):827-31. doi: 10.1016/s0140-6736(65)91372-3.
5
IMMUNOCYTOCHEMICAL AND SEROLOGIC OBSERVATIONS IN PRIMARY BILIARY CIRRHOSIS.
N Engl J Med. 1964 Nov 26;271:1123-8. doi: 10.1056/NEJM196411262712201.
6
SEROLOGICAL ABNORMALITIES IN PATIENTS WITH LIVER DISEASE.
Br Med J. 1964 Mar 7;1(5383):592-4. doi: 10.1136/bmj.1.5383.592.
7
PULMONARY TOXOPLASMOSIS?
Lancet. 1963 Nov 30;2(7318):1136-8. doi: 10.1016/s0140-6736(63)90789-x.
8
Toxoplasmosis, a general introduction.
Trans Ophthalmol Soc U K. 1958;78:99-108.
9
[Ocular toxoplasmosis and infectious hepatitis].
Dtsch Med Wochenschr. 1952 Oct 10;77(41):1250-3. doi: 10.1055/s-0028-1117206.
10
Primary biliary cirrhosis.
Proc R Soc Med. 1967 Dec;60(12):1257-60. doi: 10.1177/003591576706001205.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验