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兔在两种急性应激状态下的血浆多巴胺-β-羟化酶(DBH)活性

Plasma dopamine-beta-hydroxylase (DBH) activity in two kinds of acute stress in rabbits.

作者信息

Wasilewska E, Swiecka E

出版信息

Acta Physiol Pol. 1982 Jul-Aug;33(4):377-81.

PMID:6764083
Abstract

Changes in plasma dopamine-beta-hydroxylase (DBH) activity were studied in rabbits subjected to two kinds of acute stress: insulin-induced hypoglycaemia and fatigue. A significant elevation of DBH levels was found both 30 minutes after fatigue-induced stress (p less than 0.001) and 90 minutes after insulin injection (p less than 0.01) when compared with the control values. Responses to these two kinds of stress are reported to be mediated by the sympathetic nervous system, mainly by the adrenal glands. Thus, these results suggest that plasma DBH level is a good index of acute alterations in sympathetic activity in rabbits.

摘要

研究了经历两种急性应激(胰岛素诱导的低血糖和疲劳)的兔子血浆多巴胺-β-羟化酶(DBH)活性的变化。与对照值相比,发现疲劳诱导应激后30分钟(p<0.001)和胰岛素注射后90分钟(p<0.01)DBH水平均显著升高。据报道,对这两种应激的反应由交感神经系统介导,主要通过肾上腺。因此,这些结果表明血浆DBH水平是兔子交感神经活动急性变化的良好指标。

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