Barbosa E R, Alchorne A O, De Assis J L, Medawar J
Med Cutan Ibero Lat Am. 1982;10(5):283-8.
Myasthenia gravis associated with thymoma affecting a 76-year-old white woman is reported. Two years later, after an immunosuppressive treatment with prednisone and irradiation of the tumor, bullous lesions appeared on the skin sparing the mucosae. The histopathologic features and the direct and indirect immunofluorescence tests indicated the existence of pemphigus foliaceus. The association of Myasthenia Gravis with pemphigus foliaceus is very rare, and the present case is actually the third reported in the literature.
报告了一名76岁白人女性患伴有胸腺瘤的重症肌无力病例。两年后,在接受泼尼松免疫抑制治疗和肿瘤放疗后,皮肤出现大疱性病变,黏膜未受累。组织病理学特征以及直接和间接免疫荧光检查表明存在落叶型天疱疮。重症肌无力与落叶型天疱疮的关联非常罕见,本病例实际上是文献报道的第三例。