Henn V, Büttner-Ennever J A, Hepp K
Hum Neurobiol. 1982;1(2):77-85.
The aim of this paper is to relate recent physiological and anatomical data from Rhesus monkeys to normal function and pathology in the human oculomotor system. 1. Anatomical location of motoneurons in the oculomotor nuclei was investigated with retrograde labelling techniques, and medial rectus motoneurons were found within three different subgroups. 2. Physiological characteristics of motoneurons show a continuous distribution of different types from tonic to phasic, with tonic-phase neurons representing the majority. 3. Quantitative analysis of the firing pattern of motoneurons leads to the construction of iso-frequency curves. They show all possible eye positions for a given firing frequency in a single neuron. They give a quantitative measure for the innervation of a muscle when acting in synergy with all other muscles during fixation. The eye displacement during saccades can be described by a vector represented by a burst discharge in motoneurons, the integral of which can be used to hold the eyes in position. 4. Clinical syndromes will be discussed that can be related to anatomy and physiology.
本文旨在将恒河猴最近的生理和解剖学数据与人类动眼神经系统的正常功能及病理学联系起来。1. 运用逆行标记技术研究了动眼神经核中运动神经元的解剖位置，发现内直肌运动神经元存在于三个不同的亚组中。2. 运动神经元的生理特征显示出从紧张型到相位型不同类型的连续分布，其中紧张-相位型神经元占大多数。3. 对运动神经元放电模式的定量分析导致了等频率曲线的构建。这些曲线显示了单个神经元在给定放电频率下所有可能的眼位。它们为在注视过程中与所有其他肌肉协同作用时肌肉的神经支配提供了一种定量测量方法。扫视期间的眼位移可以用运动神经元中爆发性放电所代表的向量来描述，其积分可用于将眼睛保持在适当位置。4. 将讨论与解剖学和生理学相关的临床综合征。
