Stoka A, Noriega F G
Acta Physiol Lat Am. 1982;32(4):321-9.
When 3H-20-hydroxyecdysone was injected into Triatoma infestans during the fifth nymphal instar, it was converted to very polar metabolites (peak 1). The polar metabolites were glucuronoconjugates of 20-hydroxyecdysone. Acetylation of the conjugates followed by hydrolysis with glucuronidase gave a major labelled product: 20-hydroxyecdysone and minor peaks corresponding to a mixture of 20-hydroxyecdysone acetates. These results indicated that the 2,3,22,25-glucuronoconjugates of 20-hydroxyecdysone were the principal products in the inactivation process.
在第五若虫龄期向骚扰锥蝽注射3H-20-羟基蜕皮酮后，它会转化为极性很强的代谢产物（峰1）。这些极性代谢产物是20-羟基蜕皮酮的葡萄糖醛酸结合物。结合物经乙酰化后再用葡萄糖醛酸酶水解，得到一种主要的标记产物：20-羟基蜕皮酮以及对应于20-羟基蜕皮酮醋酸酯混合物的小峰。这些结果表明，20-羟基蜕皮酮的2,3,22,25-葡萄糖醛酸结合物是失活过程中的主要产物。
