Kondo Y
Acta Pathol Jpn. 1982;32 Suppl 1:197-209.
Our current understanding of glomerulonephritis has been established on the basis of experimental investigations. As shown in this short review, our knowledge is quite extensive, but still not enough to account for, in detail, the pathogenesis of diverse inflammatory processes occurring in the renal glomerulus. In this context, further correlated morphologic and immunopathologic studies need to be carried out. Fortunately, recent progress has been remarkable in revealing many possible chemical substances responsible for the mediation of various inflammations which may certainly encourage our experimental studies. Similarly, numerous new findings accumulated by basic immunology may be ready for application to the research about immunologic diseases, including many categories of glomerulonephritis. A modern immunologic aspect may also direct attention towards the immunologic background modulating inflammatory processes. It is expected that these possible future studies, in concert, will contribute to a comprehensive understanding of human glomerular diseases.
我们目前对肾小球肾炎的认识是在实验研究的基础上建立起来的。正如本简短综述所示，我们的知识相当广泛，但仍不足以详细解释肾小球中发生的各种炎症过程的发病机制。在此背景下，需要进一步开展相关的形态学和免疫病理学研究。幸运的是，最近在揭示许多可能介导各种炎症的化学物质方面取得了显著进展，这无疑会促进我们的实验研究。同样，基础免疫学积累的众多新发现可能已准备好应用于包括多种肾小球肾炎在内的免疫性疾病的研究。现代免疫学方面也可能将注意力引向调节炎症过程的免疫背景。预计这些未来可能的研究将共同有助于全面了解人类肾小球疾病。
