胰岛素受体与胰岛素抵抗综合征
Insulin receptors and syndromes of insulin resistance.
作者信息
Kahn C R
出版信息
Diabetes Care. 1982 May-Jun;5 Suppl 1:98-101.
PMID:6765124
Abstract
Whenever normal concentrations of insulin produce a biologic response that is less than normal, insulin resistance should be suspected. Insulin resistance may occur in many different disease states and may involve an entire organism, a single tissue or cell, or even a single metabolic pathway of insulin action. This report outlines current knowledge about the mechanism of insulin resistance, as well as specific examples of disease states in which it occurs.
摘要
每当正常浓度的胰岛素产生低于正常水平的生物学反应时，就应怀疑存在胰岛素抵抗。胰岛素抵抗可能发生在许多不同的疾病状态中，可能涉及整个机体、单个组织或细胞，甚至胰岛素作用的单个代谢途径。本报告概述了关于胰岛素抵抗机制的当前知识，以及发生胰岛素抵抗的疾病状态的具体实例。
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