Koslik S, Moscovic F, Matejícková G
Z Urol Nephrol. 1978 May;71(5):339-44.
It is reported on the changes of the thromboelastogramme, the fibrinogen level, the number of thrombocytes and the time of coagulation, which developed due to the haemodialysis with intermittent and regional heparinisation, as well as on the isolated effect of heparin, protamine and the heparin-protamine-complex. Among others the cause was discussed, why there are in some cases higher values of the time of coagulation in the patient than in the extracorporal circulation during haemodialysis. For practical reasons was emphasized that the protamine may also have a pronounced anticoagulation effect.
报告了因间歇性和局部肝素化血液透析导致的血栓弹力图、纤维蛋白原水平、血小板数量及凝血时间的变化,以及肝素、鱼精蛋白和肝素 - 鱼精蛋白复合物的单独作用。此外,还讨论了在某些情况下患者凝血时间值高于血液透析体外循环凝血时间值的原因。出于实际原因强调,鱼精蛋白也可能具有显著的抗凝作用。