Eslinger P J, Damasio A R, Van Hoesen G W
Brain Cogn. 1982 Jul;1(3):259-85. doi: 10.1016/0278-2626(82)90028-8.
We reviewed studies examining the olfaction of patients with brain damage for the purpose of discerning correlations between disordered structure and function. Patient samples included those with neurological disorders and neurosurgical interventions and recording of spontaneous or elicited neuronal activity. Brain areas involved in olfaction include the olfactory bulbs, the orbitofrontal and medial temporal cortices, the thalamus, and the amygdala. Despite recent advances in olfactory anatomy, understanding of how these structures are related to olfactory detection, discrimination, and recognition continues to be limited. Inadequate localization of brain lesions and lack of comprehensive behavioral assessment have thus far prevented a detailed account of the organization of olfaction in the human brain.
我们回顾了一些研究，这些研究旨在通过检测脑损伤患者的嗅觉来识别结构紊乱与功能之间的相关性。患者样本包括患有神经系统疾病、接受过神经外科手术干预以及记录了自发或诱发神经元活动的患者。参与嗅觉的脑区包括嗅球、眶额皮质和颞内侧皮质、丘脑以及杏仁核。尽管嗅觉解剖学最近取得了进展，但对于这些结构如何与嗅觉检测、辨别和识别相关的理解仍然有限。迄今为止，脑损伤定位不足以及缺乏全面的行为评估阻碍了对人类大脑嗅觉组织的详细描述。
