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短程放疗对膀胱移行细胞癌的生物学效应

Biological effects of short course radiation in transitional cell carcinoma of the bladder.

作者信息

Pontes J E, Pierce J M, Pokorny M, Morrison M K, Prepolec M, Devroy L

出版信息

Invest Urol. 1980 Mar;17(5):413-5.

PMID:6766913
Abstract

We evaluated the biologic effects of short course radiation therapy (1800 to 2000 rads) administered before cystectomy by placing tumors in tissue culture and observing their growth. No differences in growth were observed between irradiated and nonirradiated tumors. The minimal sublethal dose of radiation that effectively suppresses the growth of transitional cell carcinoma needs to be determined.

摘要

我们通过将肿瘤置于组织培养中并观察其生长情况,评估了在膀胱切除术前行短疗程放射治疗(1800至2000拉德)的生物学效应。未观察到照射组和未照射组肿瘤在生长方面存在差异。需要确定有效抑制移行细胞癌生长的最小亚致死剂量。

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