蛋白质交联试剂对乌贼轴突膜电流的影响。
Effect of protein cross-linking reagents on membrane currents of squid axon.
作者信息
Horn R, Brodwick M S, Eaton D C
出版信息
Am J Physiol. 1980 Mar;238(3):C127-32. doi: 10.1152/ajpcell.1980.238.3.C127.
Abstract
The effects of the protein cross-linking reagents glutaraldehyde, tannic acid, and formaldehyde were examined in voltage-clamped and internally perfused squid axons. All three reagents reduced sodium and potassium currents and reduced or abolished sodium inactivation. Glutaraldehyde and tannic acid produced an alteration of potassium current kinetics.
摘要
在电压钳制和内部灌注的枪乌贼轴突中研究了蛋白质交联试剂戊二醛、单宁酸和甲醛的作用。这三种试剂均降低了钠电流和钾电流，并降低或消除了钠失活。戊二醛和单宁酸使钾电流动力学发生了改变。
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