对家族进行完整的HLA和Bf分型。I. 混合淋巴细胞培养反应分析和连锁不平衡分型。
Complete HLA and Bf typing in families. I. Analysis of MLC responses and LD typing.
作者信息
Rubinstein P, Falk C, Martin M, Suciu-Foca N
出版信息
Transplant Proc. 1977 Mar;9(1 Suppl 1):77-81.
PMID:67684
Abstract
A triple normalization protocol for the analysis of MLC responses was evaluated using data obtained in more than 1700 triplicate reactions between the members of 17 families. The results show the method to be consistent with immunogenetic expectations. Typing responses to HTC, however, may have values identical with those of some weak one-haplotype responses and often can only be resolved by segregationanalysis.
摘要
使用从17个家族成员间的1700多次三联体反应中获得的数据，对一种用于分析混合淋巴细胞培养（MLC）反应的三联体标准化方案进行了评估。结果表明该方法与免疫遗传学预期一致。然而，对混合淋巴细胞培养（HTC）的分型反应可能与某些弱的单倍型反应的值相同，并且通常只能通过家系分析来解决。
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