巨幼细胞贫血的诊断与检查中的问题
Problems in the diagnosis and investigation of megaloblastic anemia.
作者信息
Shojania A M
出版信息
Can Med Assoc J. 1980 May 10;122(9):999-1004.
Abstract
The diagnosis of megaloblastic anemia and the differentiation of folate and vitamin B12 deficiency require, in addition to careful attention to the history and physical findings, the use of laboratory tests. In this paper the commonly ordered tests for such a diagnosis are discussed, with emphasis on the conditions that may cause false-positive or false-negative results in the complete blood count, examination of a peripheral blood smear and a bone marrow specimen, serum and erythrocyte folate assays, serum vitamin B12 assays, tests of vitamin B12 absorption and gastric analysis.
摘要
巨幼细胞贫血的诊断以及叶酸和维生素B12缺乏的鉴别，除了要仔细关注病史和体格检查结果外，还需要进行实验室检查。本文讨论了用于此类诊断的常见检查项目，重点关注全血细胞计数、外周血涂片和骨髓标本检查、血清及红细胞叶酸测定、血清维生素B12测定、维生素B12吸收试验及胃液分析中可能导致假阳性或假阴性结果的情况。
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本文引用的文献
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The value of the mean corpuscular volume (MCV) as a screening test.平均红细胞体积（MCV）作为一种筛查试验的价值。
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