生命色素的生物合成：大环的形成。
Biosynthesis of the pigments of life: formation of the macrocycle.
作者信息
Battersby A R, Fookes C J, Matcham G W, McDonald E
出版信息
Nature. 1980 May 1;285(5759):17-21. doi: 10.1038/285017a0.
DOI:10.1038/285017a0
PMID:6769048
Abstract
The organic nuclei of chlorophylls, haems, cytochromes and vitamin B12 are biosynthesised from a single tetrapyrrolic intermediate which has an unexpected, rearranged structure. The mechanism of biosynthesis of this key intermediate has now been characterised in detail. Some of the information thereby obtained is also of use in the investigation of human diseases such as the porphyrias.
摘要
叶绿素、血红素、细胞色素和维生素B12的有机核由一种具有意想不到的重排结构的单一四吡咯中间体生物合成。现在已经详细表征了这种关键中间体的生物合成机制。由此获得的一些信息也可用于诸如卟啉症等人类疾病的研究。
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