Hanke C W, Steck W D, Bergfeld W F, Valenzuela R, Weick J K, Young J R, Gross E G
Arch Dermatol. 1980 May;116(5):575-7.
A patient with Waldenström's macroglobulinemia had firm, translucent papules and nodules on the extremities. Clinically, the skin lesions were suggestive of amyloidosis cutis. Histologically, a homogeneous eosinophilic material was observed in the upper dermis and encasing the hair follicles. Special histochemical stains, electron microscopy, and immunofluorescence microscopy identified the material as IgM.
一名患有华氏巨球蛋白血症的患者四肢出现质地坚实、半透明的丘疹和结节。临床上，这些皮肤损害提示为皮肤淀粉样变。组织学检查显示，在真皮上层可见均质嗜酸性物质并包绕毛囊。特殊组织化学染色、电子显微镜检查及免疫荧光显微镜检查确定该物质为IgM。
