[Effect of carbon dioxide on respiration and phosphorylation in cerebral cortex and liver tissues].

Respiration and phosphorylation in the brain and liver tissues were studied as affected by hypercapnia. It is found that the activity of respiration and phosphorylation in rats changes after their 30 min stay in the gas medium containing 18-19% of CO2. The degree and direction of the changes depend on both specificity of the studied tissue and individual sensitivity of animals to hypoxic hypoxia. In the brain the phosphorylating intensity with hypercapnia rises, but in the liver, vice versa, it is lower as compared to the level of this process in control animals. In rats high-resistant to hypoxia an increase in the energy efficiency of oxidation in the brain tissue was reached at a less oxygen uptake than in the nonresistant animals.