Simonovits I, Timár I, Bajtai G
Vox Sang. 1980;38(3):161-4. doi: 10.1111/j.1423-0410.1980.tb02344.x.
The occurrence of Rh immunization was investigated in 386 secundigravidae whose first pregnancy was terminated by induced abortion and who were not given anti-D immunoglobulin after the induced abortion. Of these, 6 (1.57%) already proved to be seropositive at the beginning of their second pregnancy, another 6 (1.57%) became positive by the end of the second pregnancy, i.e. 3.14% altogether as demonstrated with papain-treated RBC. If instead the indirect antiglobulin (Coombs) test was used, 3 women (0.77%) proved to be positive at the beginning and 9 (2.31%) at the end of the second pregnancy. Supposing that 0.5% of the secundigravidae became immunized during the second pregnancy, the rate of immunization after induced abortion in non-protected cases may be calculated to be 2.64% using the papain technique and 1.81% when the antiglobulin test is applied.
对386例经人工流产终止第一胎妊娠且人工流产后未注射抗-D免疫球蛋白的经产妇进行了Rh免疫情况的调查。其中，6例（1.57%）在第二次妊娠开始时已被证实血清学阳性，另有6例（1.57%）在第二次妊娠结束时转为阳性，即使用木瓜蛋白酶处理的红细胞检测时，总计3.14%。若改用间接抗球蛋白（库姆斯）试验，3例女性（0.77%）在第二次妊娠开始时被证实为阳性，9例（2.31%）在第二次妊娠结束时为阳性。假设0.5%的经产妇在第二次妊娠期间发生免疫，使用木瓜蛋白酶技术计算未受保护情况下人工流产后的免疫率为2.64%，应用抗球蛋白试验时为1.81%。
