长期使用格陵兰治疗淋病的方法。
Prolonged use of the Greenland method of treatment of gonorrhoea.
作者信息
Evans A J, Morrison G D, Price D J
出版信息
Br J Vener Dis. 1980 Apr;56(2):88-91. doi: 10.1136/sti.56.2.88.
Abstract
Of 1081 patients with gonorrhoea treated with probenecid 1 g orally and benzyl penicillin 5 megaunits intramuscularly, 96.7% were cured and no complications were encountered. This treatment regimen was associated with a pronounced reduction in the proportion of gonococcal strains showing diminished sensitivity to penicillin, from 51% to between 4% and 14% over a period of four years. When this treatment method was abandoned, however, the percentage of less sensitive strains rose to 33% over the following 18 months.
摘要
对1081例淋病患者采用丙磺舒1克口服加苄星青霉素500万单位肌内注射进行治疗，96.7%的患者治愈，且未出现并发症。在四年时间里，这种治疗方案使对青霉素敏感性降低的淋球菌菌株比例显著下降，从51%降至4%至14%之间。然而，当放弃这种治疗方法后，在接下来的18个月里，敏感性较低菌株的比例升至33%。
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本文引用的文献
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2
A comparison of the in vitro sensitivity of gonococci to penicillin with the results of treatment.淋病双球菌对青霉素的体外敏感性与治疗结果的比较。
Br J Vener Dis. 1958 Jun;34(2):70-8; discussion 78-82. doi: 10.1136/sti.34.2.70.
3
Sensitivity of strains of gonococci to penicillin, sulphathiazole, and streptomycin.淋病双球菌菌株对青霉素、磺胺噻唑和链霉素的敏感性。
Br Med J. 1958 May 10;1(5079):1091-2. doi: 10.1136/bmj.1.5079.1091.
4
Intramuscular injection of procaine penicillin combined with oral administration of chloramphenicol in the treatment of gonorrhoea.肌肉注射普鲁卡因青霉素联合口服氯霉素治疗淋病。
Br J Vener Dis. 1966 Jun;42(2):107-9. doi: 10.1136/sti.42.2.107.
5
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Br J Vener Dis. 1969 Jun;45(2):144-8. doi: 10.1136/sti.45.2.144.
6
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7
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