Sansonetti P, David M, Toucas M
C R Seances Acad Sci D. 1980 Mar 31;290(13):879-82.
Transition from virulent phase I to non virulent phase II in five strains of Shigella sonnei was studied by immunofluorescence and plasmid electrophoresis. High frequency loss of phase I specific antigens was observed by use of fluorescent phase specific antibodies. Agarose gel electrophoresis of bacterial lysates showed that transition from phase I to phase II is associated with the loss of extrachromosomal DNA.
通过免疫荧光和质粒电泳研究了五株宋内志贺氏菌从有毒力的I期向无毒力的II期的转变。使用荧光相特异性抗体观察到I期特异性抗原的高频丢失。细菌裂解物的琼脂糖凝胶电泳表明，从I期到II期的转变与染色体外DNA的丢失有关。
