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[1974 - 1975年流感病毒流行株抗原特性分析]

[Analysis of the antigenic properties of strains of influenza virus that caused the epidemic of 1974-1975].

作者信息

Zakstel'ska L Ia, Shenderovich S F, Molibog E V, Iakhno M A

出版信息

Vopr Virusol. 1976 Nov-Dec(6):702-6.

PMID:67716
Abstract

The etiology of influenza epidemic of 1974-1975 in the USSR was studied. The influenza viruses isolated from patients in the period of the 1974-1975 epidemic were tested in the hemagglutination-inhibition, neuraminidase activity-inhibition, immunoadsorption and biological neutralization tests. The majority of the strains tested were shown to be similar to the new antigenic variant A/Port Chalmers/1/73. It means that the strains of A/Port Chalmers/1/73 variant occurred epidemically in this region only in the winter of 1974-1975. The greatest differences between the new isolates and previously circulating strains of A/England/42/72 variant were observed in biologic neutralization tests.

摘要

对苏联1974 - 1975年流感流行的病因进行了研究。对在1974 - 1975年流行期间从患者身上分离出的流感病毒进行了血凝抑制、神经氨酸酶活性抑制、免疫吸附和生物中和试验。所检测的大多数毒株显示与新的抗原变异株A/Port Chalmers/1/73相似。这意味着A/Port Chalmers/1/73变异株仅在1974 - 1975年冬季在该地区呈流行性出现。在生物中和试验中观察到新分离株与先前流行的A/England/42/72变异株之间存在最大差异。

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