Trachtenberg M C, Sapirstein V S
Neurochem Res. 1980 May;5(5):573-81. doi: 10.1007/BF00964994.
Total and specific carbonic anhydrase activity was measured for 24 structures of the rat central and peripheral nervous system. In the CNS, white matter or regions containing largely white matter show a neuraxial distribution of enzyme activity; more cephalad structures display more activity. Gray matter regions do not show a rostrocaudal distribution and usually have lower activity than adjacent myelin-containing structures. PNS tissue shows neither the white-gray differences nor the rostrocaudal profile of CNS tissue. Subcellular fractionation of 18 regions of the CNS suggest that the predominance of membrane-bound carbonic anhydrase (60% of the total activity and independent of its magnitude) is a unique characteristic of all regions of the central nervous system.
对大鼠中枢和外周神经系统的24个结构进行了总碳酸酐酶活性和特异性碳酸酐酶活性的测定。在中枢神经系统中，白质或主要包含白质的区域呈现酶活性的神经轴分布；更靠头端的结构显示出更高的活性。灰质区域没有显示出从头至尾的分布，并且其活性通常低于相邻的含髓鞘结构。外周神经系统组织既没有显示出中枢神经系统组织的白质-灰质差异，也没有显示出从头至尾的分布特征。对中枢神经系统18个区域的亚细胞分级分离表明，膜结合碳酸酐酶占主导地位（占总活性的60%，且与活性大小无关）是中枢神经系统所有区域的一个独特特征。
