Meis P J, Hall M, Marshall J R, Hobel C J
Am J Obstet Gynecol. 1978 Jul 1;131(5):509-13. doi: 10.1016/0002-9378(78)90111-4.
The significance of MSAL as a sign of fetal distress is controversial. To better assess this condition, we present a classification of MSAL based on the timing and quantity of meconium passed and divided into early light, early heavy, and late passage of MSAL. By means of this classification with a problem-oriented risk assessment system, 2,933 pregnancies were prospectively evaluated during labor. The incidence of meconium passage was 22 per cent, of which early light constituted 53.6 per cent, early heavy 25.2 per cent, and late passage 21.2 per cent. Early heavy MSAL is associated with increased fetal and neonatal morbidity and death, and with a number of antecedent obstetric problems. Late passage of MSAL encountered no perinatal losses, but is associated with increased neonatal morbidity occurring late in labor. Early light MSAL, constituting over half of all our meconium group of patients, is not associated with any increased intrapartum or neonatal morbidity or death. This classification of MSAL is an effective tool for risk assessment during labor.
胎粪吸入综合征(MSAL)作为胎儿窘迫征象的意义存在争议。为了更好地评估这种情况,我们根据胎粪排出的时间和量对MSAL进行了分类,分为早期少量、早期大量和晚期排出MSAL。通过这种分类以及面向问题的风险评估系统,在分娩期间对2933例妊娠进行了前瞻性评估。胎粪排出的发生率为22%,其中早期少量占53.6%,早期大量占25.2%,晚期排出占21.2%。早期大量MSAL与胎儿和新生儿发病率及死亡率增加以及一些先前的产科问题相关。晚期排出MSAL未出现围产期死亡,但与分娩后期新生儿发病率增加相关。早期少量MSAL占我们所有胎粪组患者的一半以上,与产时或新生儿发病率及死亡率增加无关。这种MSAL分类是分娩期间风险评估的有效工具。