Carell E F, Seeger J W
Biochem J. 1980 May 15;188(2):573-6. doi: 10.1042/bj1880573.
The ribonucleotide reductase activities in vitamin B12-sufficient and -deficient cells of Euglena gracilis were measured. We found that the cells progress into vitamin B12 deficiency the enzyme activity increases, reaching a maximum value of 20-fold in advanced deficiency. No signigicant differences in the activities were found to result as a consequence of different growth conditions. We propose that the increased activity in vitamin B12-deficient cells is due to an increase in enzyme protein.
对纤细裸藻中维生素B12充足和缺乏的细胞中的核糖核苷酸还原酶活性进行了测量。我们发现，随着细胞进入维生素B12缺乏状态，该酶的活性增加，在严重缺乏时达到最大值，为原来的20倍。未发现不同生长条件导致活性有显著差异。我们认为维生素B12缺乏细胞中活性增加是由于酶蛋白增加所致。
