两名患有先天性低促性腺激素性性腺功能减退和嗅觉缺失（卡尔曼综合征）的“生育无能的宦官”中的HLA相容性父子关系

HLA-compatible paternity in two "fertile eunuchs" with congenital hypogonadotropic hypogonadism and anosmia (the Kallmann syndrome).

作者信息

Rogol A D, Mittal K K, White B J, McGinniss M H, Lieblich J M, Rosen S W

出版信息

J Clin Endocrinol Metab. 1980 Aug;51(2):275-9. doi: 10.1210/jcem-51-2-275.

Abstract

Two men are described who fulfill the criteria for both the Kallmann and the fertile eunuch syndrome, and we report the erythrocyte and HLA phenotypes of these men and their children. There were no paternal exclusions noted in red blood cell phenotypes encompassing seven separate red cell systems. The HLA phenotypes indicate that the probability that these men were the fathers of the children was greater than 99.99%.

摘要

本文描述了两名符合卡尔曼综合征和生育期宦官综合征标准的男性，并报告了这些男性及其子女的红细胞和人类白细胞抗原（HLA）表型。在涵盖七个独立红细胞系统的红细胞表型中，未发现父系排除情况。HLA表型表明，这些男性是孩子父亲的概率大于99.99%。