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[抗癫痫制剂治疗三叉神经痛患者的疗效比较]

[Comparative effectiveness of antiepileptic preparations in the treatment of patients with trigeminal neuralgia].

作者信息

Karlov V A, Savitskaia O N

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(4):530-5.

PMID:6773276
Abstract

A comparative analysis of the effect from using the antiepileptic drugs tegretol, morpholep, sucsilep, trimethin, chlonazepam, and sodium valproate in 258 patients with trigeminal neuralgia was carried out. In half of the cases long-time follow-up observations were made. The results of the treatment were analyzed with reference to the time in which the therapeutic effect appeared and reached the maximum, as well as to the stability of the therapeutic remission obtained. Causes of failure of the therapy in some patients and the drugs' side-effects were analyzed.

摘要

对258例三叉神经痛患者使用抗癫痫药物卡马西平、吗氯贝胺、舒噻美、三甲双酮、氯硝西泮和丙戊酸钠的效果进行了对比分析。其中一半病例进行了长期随访观察。参照治疗效果出现并达到最大值的时间以及所获得的治疗缓解的稳定性对治疗结果进行了分析。分析了部分患者治疗失败的原因以及药物的副作用。

相似文献

1
[Comparative effectiveness of antiepileptic preparations in the treatment of patients with trigeminal neuralgia].[抗癫痫制剂治疗三叉神经痛患者的疗效比较]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(4):530-5.
2
[Treatment of trigeminal neuralgia with spasmolytics].[使用解痉药治疗三叉神经痛]
Sov Med. 1974 Sep;0(9):21-5.
3
Oxcarbazepine monotherapy in carbamazepine-unresponsive trigeminal neuralgia.奥卡西平单药治疗对卡马西平无反应的三叉神经痛
J Clin Neurosci. 2008 May;15(5):516-9. doi: 10.1016/j.jocn.2007.04.010. Epub 2008 Apr 2.
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Anticonvulsant drugs for management of pain: a systematic review.用于疼痛管理的抗惊厥药物:一项系统评价
BMJ. 1995 Oct 21;311(7012):1047-52. doi: 10.1136/bmj.311.7012.1047.
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Antiepileptic drugs: indications other than epilepsy.抗癫痫药物:癫痫以外的适应症。
Epileptic Disord. 2004 Jun;6(2):57-75.
6
[Experience in the treatment of trigeminal neuralgia using Tegretol].[使用卡马西平治疗三叉神经痛的经验]
Dtsch Gesundheitsw. 1971 Dec 2;26(49):2333-5.
7
[Short-term and long-term effects of psychotropic drugs in the treatment of trigeminal neuralgia (author's transl)].精神药物治疗三叉神经痛的短期和长期效果(作者译)
Nervenarzt. 1979 Sep;50(9):601-4.
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Baclofen in the treatment of trigeminal neuralgia: double-blind study and long-term follow-up.巴氯芬治疗三叉神经痛:双盲研究及长期随访
Ann Neurol. 1984 Mar;15(3):240-4. doi: 10.1002/ana.410150306.
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Is carbamazepine less effective in the treatment of trigeminal neuralgia when prescribed by oral and maxillofacial surgeons?当由口腔颌面外科医生开具处方时,卡马西平治疗三叉神经痛的效果是否较差?
Anesth Prog. 1997 Spring;44(2):55-8.
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Influence of piracetam on anticonvulsant effects of antiepileptic drugs in mice.吡拉西坦对小鼠抗癫痫药物抗惊厥作用的影响。
Act Nerv Super (Praha). 1990 Mar;32(1):55-6.

引用本文的文献

1
Trigeminal neuralgia : a guide to drug choice.三叉神经痛:药物选择指南。
CNS Drugs. 1997 Feb;7(2):98-110. doi: 10.2165/00023210-199707020-00002.
2
Anticonvulsants for neuropathic pain syndromes: mechanisms of action and place in therapy.用于神经性疼痛综合征的抗惊厥药:作用机制及治疗地位
Drugs. 2000 Nov;60(5):1029-52. doi: 10.2165/00003495-200060050-00005.