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神经冲动编码的一种假说。

A hypothesis of the code of nerve impulses.

作者信息

Moroz P E

出版信息

Acta Biotheor. 1980;29(2):101-9. doi: 10.1007/BF00046375.

Abstract

There is probably only one information system in living nature - the macromolecular system including DNA, RNA and protein. Its unity for the genetic and nervous activity can be followed in the storage of information (heredity, memory) and in its processing (recombination and selection of both genetic and mental information). According to the hypothesis of the code of nerve impulses, nucleotide triplets of the nucleus, or more likely amino acids of the surface protein of the impulse generating area of a neuron, generate a limitd variety of interspike intervals so that each amino acid corresponds to a certain interspike interval and this particular interval initiates by means of a specific neurotransmitter, the synthesis of the same amno acid (or nucleotide triplet) in the postsynaptic neuron. Thus, a series of impulses produces in the postsynaptic neuron a sequence of amino acids in a form of a polypeptide identical to the polypeptide of the presynaptic neuron.

摘要

在生物界中可能只有一种信息系统——包括DNA、RNA和蛋白质的大分子系统。其在遗传和神经活动方面的统一性体现在信息存储(遗传、记忆)及其处理过程(遗传信息和心理信息的重组与选择)中。根据神经冲动编码假说,细胞核中的核苷酸三联体,或者更有可能是神经元冲动产生区域表面蛋白质的氨基酸,产生有限种类的峰间间隔,使得每个氨基酸对应于特定的峰间间隔,并且这个特定间隔通过特定的神经递质引发突触后神经元中相同氨基酸(或核苷酸三联体)的合成。因此,一系列冲动在突触后神经元中产生以与突触前神经元多肽相同形式的氨基酸序列。

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