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脑干对耳蜗电刺激的反应。

Brainstem responses to electrical stimulation of cochlea.

作者信息

Dobie R A, Kimm J

出版信息

Arch Otolaryngol. 1980 Sep;106(9):573-7. doi: 10.1001/archotol.1980.00790330053015.

DOI:10.1001/archotol.1980.00790330053015
PMID:6773514
Abstract

We performed a brainstem evoked response (BSER) study to evaluate the extent to which electrical stimulation of the cochlea was conducted centrally by facial, vestibular, and cochlear nerves. Short-term experiments were performed in three monkeys: via a postauricular approach to the round window, a molded Silastic multielectrode prosthesis was placed in the scala tympani. The BSER was recorded to threshold and suprathreshold biphasic electrical pulses delivered to the implant electrodes. A middle cranial fossa dissection was then carried out, exposing the nerves of the internal auditory canal from above. Facial and vestibular neurotomy had no significant effect on BSER, while cochlear nerve section abolished the response. In one animal, blunt pressure on the cochlear nerve caused a reversible loss of electrically evoked BSER. Electrically evoked BSER probably depends on propagated impulses in the cochlear nerve.

摘要

我们进行了一项脑干诱发反应(BSER)研究,以评估耳蜗的电刺激通过面神经、前庭神经和蜗神经向中枢传导的程度。在三只猴子身上进行了短期实验:通过耳后入路至圆窗,将一个模制的硅橡胶多电极假体置于鼓阶。记录BSER对传递至植入电极的阈下和阈上双相电脉冲的反应。然后进行中颅窝解剖,从上方暴露内耳道的神经。面神经和前庭神经切断术对BSER无显著影响,而蜗神经切断则消除了反应。在一只动物中,对蜗神经的钝性压迫导致电诱发的BSER可逆性丧失。电诱发的BSER可能取决于蜗神经中传播的冲动。

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