[消炎痛对催乳素促乳作用的影响]

[Effect of indomethacin on the lactogenic action of prolactin].

作者信息

Houdebine L M, Lacroix M C

出版信息

Biochimie. 1980;62(7):441-4. doi: 10.1016/s0300-9084(80)80060-5.

Abstract

The action of indomethacin on the lactogenic activity of prolactin has been evaluated usind the technique of rabbit mammary gland organ culture. Indomethacin is totally unable to inhibit prolactin action as estimated by lactose synthetase activity and casein synthesis. These data suggest, as opposed to previous works, that prostaglandins are not involved in the mechanism of prolactin action on lactogenesis.

摘要

已采用兔乳腺器官培养技术评估了吲哚美辛对催乳素泌乳活性的作用。根据乳糖合成酶活性和酪蛋白合成估计，吲哚美辛完全无法抑制催乳素的作用。与先前的研究相反，这些数据表明前列腺素不参与催乳素对泌乳作用的机制。