Page R B, Funsch D J, Brennan R W, Hernández M J
Brain Res. 1980 Sep 22;197(2):532-7. doi: 10.1016/0006-8993(80)91142-7.
Choroid plexus blood flow was measured in 29 adult female sheep using the radioactive microsphere technique. Basal blood flow, response to change in arterial carbon dioxide tension, and response to change in mean arterial blood pressure were determined. The results were compared to cerebral cortical blood flow values in the same sheep. Mean choroid plexus blood flow was 601 ml/100 g/min under basal conditions. Choroid plexus blood flow fell 31% with hypocarbia, a reduction comparable to that seen in cortex. With hypercarbia choroid plexus blood flow rose only 27% whereas cortical blood flow increased by 199%. Unlike cortical blood flow, choroid plexus blood flow fell significantly with pharmacogenic hypertension. The latter finding may reflect the absence of a blood-brain barrier in choroid plexus.
采用放射性微球技术对29只成年雌性绵羊的脉络丛血流进行了测量。测定了基础血流、对动脉二氧化碳分压变化的反应以及对平均动脉血压变化的反应。将结果与同一只绵羊的大脑皮质血流值进行了比较。基础条件下脉络丛平均血流为601毫升/100克/分钟。低碳酸血症时脉络丛血流下降31%，这一降幅与皮质中所见相当。高碳酸血症时脉络丛血流仅上升27%，而皮质血流增加了199%。与皮质血流不同，药物性高血压时脉络丛血流显著下降。后一发现可能反映了脉络丛中不存在血脑屏障。
