Langer R, Fefferman M, Gryska P, Bergman K
Can J Microbiol. 1980 Feb;26(2):274-8. doi: 10.1139/m80-045.
Chemotaxis of the bacterium Escherichia coli and the planarian Dugesia dorotocephala toward a variety of substances impregnated in sustained-release polymers has been demonstrated. Tests were carried out in soft agar and in aqueous medium with highly consistent results. The simplicity of this method may make it particularly useful for rapid qualitative screening of new wild-type and mutant strains of bacteria for chemotaxis toward nonmetabolites. The cost, ease of fabrication, and the facility with which they can be utilized in test systems suggest that these sustained-release vehicles will provide a new and general method of creating concentration gradients to study chemotaxis.
已证明大肠杆菌和涡虫多目涡虫对浸渍在缓释聚合物中的多种物质具有趋化性。在软琼脂和水性介质中进行了测试，结果高度一致。这种方法的简单性可能使其特别适用于对新型野生型和突变型细菌菌株针对非代谢物的趋化性进行快速定性筛选。这些缓释载体的成本、易于制造以及可在测试系统中使用的便利性表明，它们将提供一种全新的通用方法来创建浓度梯度以研究趋化性。
