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蝎子蜇伤后急性肾衰竭

Acute renal failure following scorpion sting.

作者信息

Malhotra K K, Mirdehghan C M, Tandon H D

出版信息

Am J Trop Med Hyg. 1978 May;27(3):623-6. doi: 10.4269/ajtmh.1978.27.623.

DOI:10.4269/ajtmh.1978.27.623
PMID:677374
Abstract

Fifteen cases of acute renal failure follwoing scorpion sting were studied. The onset of disease was characterized by the occurrence of hemoglobinuria within 24 h of the sting. Most of the patients developed oliguria, edema, hemolytic anemia, and hemolytic jaundice. Renal failure developed within a few days after the sting, and in five patients was severe enough to need dialysis. The onset of diuresis in oliguric patients occurred between 6 and 21 days following the sting. Renal biopsies were possible in four cases and showed mesangial proliferation, variable degrees of tubular changes, and mild interstitial infiltration. The pathogenesis of acute renal failure in these patients is discussed

摘要

对15例蝎子蜇伤后发生急性肾衰竭的病例进行了研究。疾病发作的特点是蜇伤后24小时内出现血红蛋白尿。大多数患者出现少尿、水肿、溶血性贫血和溶血性黄疸。肾衰竭在蜇伤后几天内发生,5例患者病情严重到需要透析。少尿患者在蜇伤后6至21天出现利尿。4例患者可行肾活检,显示系膜增生、不同程度的肾小管改变和轻度间质浸润。讨论了这些患者急性肾衰竭的发病机制。

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