Dewar C L, Lowenthal R M
Acta Haematol. 1980;64(1):53-7. doi: 10.1159/000207210.
Electron microscopy of a new variant of congenital dyserythropoietic anaemia type II has yielded several unexpected results. The remarkable features include the relatively high percentage of erythrocytes with peripheral cisternae, the involvement of all bone marrow precursor cells, and the presence of ultrastructural defects in the granulocytes and platelets and on the cell surface of the erythrocytes. Experiments with vinblastine showed that this drug was capable of producing (in vitro) strikingly similar ultrastructural defects in healthy erythrocytes.
对II型先天性红细胞生成异常性贫血的一种新变体进行电子显微镜检查产生了几个意想不到的结果。显著特征包括外周池红细胞的比例相对较高、所有骨髓前体细胞均受累，以及粒细胞、血小板和红细胞细胞表面存在超微结构缺陷。用长春花碱进行的实验表明，这种药物能够（在体外）在健康红细胞中产生极为相似的超微结构缺陷。
