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脑肿瘤激光手术评估

Evaluation of brain tumour laser surgery.

作者信息

Hara M, Takeuchi K, Okada J, Takizawa T, Matsumoto M

出版信息

Acta Neurochir (Wien). 1980;53(3-4):141-9. doi: 10.1007/BF02074786.

Abstract

A surgical carbon dioxide laser unit (laser) has been used since 1977 in twenty-five cases of various brain tumours, including ten meningiomas (four sphenoid ridge, two parasagittal, two falx, one olfactory, one posterior fossa), eleven gliomas (seven glioblastoma, four astrocytoma), two metastatic brain tumours, one haemangioblastoma, and one arteriovenous malformation (AVM). The criteria for laser use, as based on evaluation and location of meningioma, were: grade 1, convenient but adjuvant; grade 2, also necessary; grade 3, indispensable. The laser is obligatory in sphenoid ridge meningioma in order to peel the tumour away from the internal carotid artery, middle cerebral artery, cavernous sinus ect. The grade of necessity for laser use is therefore either 2 or 3. In convexity or parasagittal meningioma, on the other hand, the necessity grade is either 1 or 2. In the glioma group hemorrhage in seven cases of glioblastoma was easily laser-controled, and the tumours were wasted away in a short time through vaporization, with minimum mechanical effect on adjacent tissue. The laser is therrefore very useful in cases of glioma, especially glioblastoma, considering the shortened operating time, decreased blood loss, and extended area of tumour resection. Laser surgery is proposed as being most appropriate, mainly for its vaporizing and coagulating functions, in cases of brain tumour involving the elderly and poor risk cases.

摘要

自1977年以来,一台外科二氧化碳激光设备(激光)已用于25例各种脑肿瘤的治疗,其中包括10例脑膜瘤(4例蝶骨嵴、2例矢状窦旁、2例大脑镰、1例嗅沟、1例后颅窝)、11例神经胶质瘤(7例胶质母细胞瘤、4例星形细胞瘤)、2例脑转移瘤、1例血管母细胞瘤和1例动静脉畸形(AVM)。基于脑膜瘤的评估和位置,激光使用标准如下:1级,方便但为辅助手段;2级,也有必要;3级,不可或缺。对于蝶骨嵴脑膜瘤,为了将肿瘤从颈内动脉、大脑中动脉、海绵窦等部位剥离,激光是必不可少的。因此,激光使用的必要性等级为2级或3级。另一方面,对于凸面或矢状窦旁脑膜瘤,必要性等级为1级或2级。在神经胶质瘤组中,7例胶质母细胞瘤的出血很容易通过激光控制,肿瘤通过汽化在短时间内缩小,对相邻组织的机械影响最小。因此,考虑到手术时间缩短、失血量减少和肿瘤切除范围扩大,激光在神经胶质瘤,尤其是胶质母细胞瘤的治疗中非常有用。对于涉及老年人和高危病例的脑肿瘤,主要因其汽化和凝固功能,建议采用激光手术最为合适。

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