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Br Heart J. 1980 Aug;44(2):175-8. doi: 10.1136/hrt.44.2.175.
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本文引用的文献

1
EFFECT OF CORONARY VASODILATOR DRUGS ON RETROGRADE FLOW IN AREAS OF CHRONIC MYOCARDIAL ISCHEMIA.冠状动脉扩张剂对慢性心肌缺血区域逆向血流的影响。
Circ Res. 1964 Oct;15:355-64. doi: 10.1161/01.res.15.4.355.
2
Myocardial perfusion imaging with radioactive-labeled particles injected directly into the coronary circulation of patients with coronary artery disease.通过将放射性标记颗粒直接注入冠状动脉疾病患者的冠状动脉循环进行心肌灌注成像。
Circulation. 1971 Nov;44(5):851-65. doi: 10.1161/01.cir.44.5.851.
3
Effect of nitrate infusions on the systemic and coronary circulations following acute experimental myocardial infarction in the intact dog.硝酸盐输注对完整犬急性实验性心肌梗死后体循环和冠脉循环的影响。
Am J Cardiol. 1972 Sep;30(4):362-70. doi: 10.1016/0002-9149(72)90566-8.
4
Safety of the direct coronary injection of radiolabeled particles.放射性标记颗粒直接冠状动脉注射的安全性。
J Nucl Med. 1974 Jan;15(1):2-6.
5
Failure of intracoronary nitroglycerin to alleviate pacing-induced angina.冠状动脉内硝酸甘油未能缓解起搏诱发的心绞痛。
Circulation. 1972 Nov;46(5):880-9. doi: 10.1161/01.cir.46.5.880.
6
Myocardial perfusion color scintigraphy with MAA.用大颗粒聚合人血清白蛋白进行心肌灌注彩色闪烁显像。
Radiology. 1973 Nov;109(2):369-80. doi: 10.1148/109.2.369.
7
Differential response of large and small coronary arteries to nitroglycerin and angiotensin. Autoregulation and tachyphylaxis.大、小冠状动脉对硝酸甘油和血管紧张素的不同反应。自动调节和快速耐受性。
Circ Res. 1973 Oct;33(4):445-53. doi: 10.1161/01.res.33.4.445.
8
Intraoperative coronary collateral function in patients with coronary occlusive disease. Nitroglycerin responsiveness and angiographic correlations.冠状动脉闭塞性疾病患者的术中冠状动脉侧支循环功能。硝酸甘油反应性及血管造影相关性。
Circulation. 1974 Feb;49(2):298-308. doi: 10.1161/01.cir.49.2.298.
9
The effects of nitroglycerin on coronary collaterals and myocardial contractility.硝酸甘油对冠状动脉侧支循环和心肌收缩力的影响。
J Clin Invest. 1973 Nov;52(11):2836-47. doi: 10.1172/JCI107479.
10
Myocardial imaging with indium- 113m- and technetium-99m-macroaggregated albumin. New procedure for identification of stress-induced regional ischemia.
Am J Cardiol. 1975 Mar;35(3):380-9. doi: 10.1016/0002-9149(75)90031-4.

冠状动脉内注射硝酸甘油对人体心肌侧支循环灌注分布的影响。

Effect of intracoronary glyceryl trinitrate on perfusion distribution in the collateralised human myocardium.

作者信息

Wald R W, Sternberg L, Feiglin D H, Morch J E

出版信息

Br Heart J. 1980 Aug;44(2):175-8. doi: 10.1136/hrt.44.2.175.

DOI:10.1136/hrt.44.2.175
PMID:6775646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC482378/
Abstract

The effect on myocardial perfusion distribution of intracoronary glyceryl trinitrate in a dose (60 micrograms) insufficient to cause alterations in systemic blood pressure or heart rate was studied in eight patients with angiographically demonstrated collaterals from the left coronary system to the distal right coronary artery. Double isotope imaging using technetium-99m and iodine-131 labelled albumin macroaggregates allowed each patient to serve as his own control. The reproducibility of the imaging and data handling techniques was shown in 12 control patients. Glyceryl trinitrate caused a significant diminution in the collateral-mediated fractional perfusion while increasing that of the native coronary bed.

摘要

在8例经血管造影证实有从左冠状动脉系统至右冠状动脉远端侧支循环的患者中，研究了冠状动脉内注入剂量为60微克的硝酸甘油对心肌灌注分布的影响，该剂量不足以引起全身血压或心率改变。采用锝-99m和碘-131标记的白蛋白大聚合体进行双同位素成像，使每位患者可作为自身对照。在12例对照患者中显示了成像和数据处理技术的可重复性。硝酸甘油使侧支循环介导的灌注分数显著降低，同时增加了自身冠状动脉床的灌注分数。