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正在经历加速吸收的创伤性人类乳牙中的黏多糖酶活性:分离与鉴定

Mucopolysaccharidase activity in traumatized human deciduous teeth undergoing accelerated resorption: isolation and characterization.

作者信息

Alexander S A, Swerdloff M

出版信息

J Oral Pathol. 1980 May;9(3):121-8. doi: 10.1111/j.1600-0714.1980.tb00368.x.

DOI:10.1111/j.1600-0714.1980.tb00368.x
PMID:6776246
Abstract

Mucopolysaccharidase activity was observed in traumatized human decidous teeth. Histochemical analysis of the periodontal ligaments from these teeth revealed a loss of film substrate metachromasia during incubation, indicating enzyme activity. Routine histology of these ligaments showed the presence of an inflammatory infiltrate throughout this tissue. Biochemical analysis of the ligaments revealed a 10-fold increase of enzyme activity when incubation time was increased from 1 to 8 h. When compared to the enzyme activity measured during physiologic resorption, activity was increased. This suggests that the presence of an inflammatory infiltrate not observed in the tissues undergoing physiologic resorption may be responsible for the rapid resorption seen in traumatized deciduous teeth.

摘要

在受创伤的人乳牙中观察到粘多糖酶活性。对这些牙齿的牙周韧带进行组织化学分析,发现在孵育过程中膜底物异染性丧失,表明存在酶活性。这些韧带的常规组织学检查显示整个组织存在炎性浸润。对韧带的生化分析表明,当孵育时间从1小时增加到8小时时,酶活性增加了10倍。与生理吸收过程中测得的酶活性相比,活性有所增加。这表明在生理吸收的组织中未观察到的炎性浸润可能是导致受创伤乳牙快速吸收的原因。

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Mucopolysaccharidase activity in traumatized human deciduous teeth undergoing accelerated resorption: isolation and characterization.正在经历加速吸收的创伤性人类乳牙中的黏多糖酶活性:分离与鉴定
J Oral Pathol. 1980 May;9(3):121-8. doi: 10.1111/j.1600-0714.1980.tb00368.x.
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