Durrant B S, Eisen E J, Ulberg L C
J Reprod Fertil. 1980 Jul;59(2):329-39. doi: 10.1530/jrf.0.0590329.
Single trait selection of mice for either large body size or large litter size resulted in an increased ovulation rate because of possible enhanced ovarian sensitivity to gonadotrophins. There was no difference in pre-implantation embryonic survival in either of the selected lines when compared to control mice. Selection for body weight did not alter post-implantation embryo survival, but fewer fetuses were lost after implantation in the litter size line compared to the control line. Index selection for large body size and small litter size did not change ovulation rate but increased pre- and post-implantation embryonic mortality. Selection for small body size and large litter size increased ovulation rate and decreased early embryonic death.
对小鼠进行单一性状选择，选择体型大或产仔数多的小鼠，由于卵巢对促性腺激素的敏感性可能增强，导致排卵率增加。与对照小鼠相比，所选品系中任何一个的植入前胚胎存活率均无差异。选择体重并未改变植入后胚胎的存活率，但与对照品系相比，产仔数品系中植入后丢失的胎儿较少。对体型大且产仔数少进行指数选择并未改变排卵率，但增加了植入前和植入后胚胎的死亡率。选择体型小且产仔数多增加了排卵率并降低了早期胚胎死亡。
