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[Ulstrastructural study of various evolutive stages of pityriasis versicolor (author's transl)].

作者信息

Boiron G, Surléve-Bazeille J E, Gauthier Y, Maleville J

出版信息

Ann Dermatol Venereol. 1978 Feb;105(2):141-9.

PMID:677683
Abstract

Small size, less numerous and sometimes clustered melanosomes, were seen within the melanocytes. The others organites alos showed abnormalities: smaller mitochondria, abundant cytofilaments. Sometimes total degeneration of the melanocyte was seen. These alterations are variable, depending upon the evolutive stage of pityriasis versicolor: either hypopigmented undergoing treatment or not, or hyperpigmented. Reactions of several cellular types of the dermoepidermal unit could be observed: more numerous Langerhans cells located near the base of the epidermis, abundant nerve fibers in the superficial dermis and active fibroblasts of foetal type. A slight inflammatory infiltrate was present in some cases. It is suggested that a toxic effect of the fungus is responsible for the changes of the morphological aspects of the melanocyte.

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