通过血浆置换和免疫抑制治疗联合控制一名患有抑制物的血友病患者的危及生命的出血。
Control of life-threatening bleeding by combined plasmapheresis and immunosuppressive treatment in a haemophiliac with inhibitors.
作者信息
Révész T, Mátyus J, Goldschmidt B, Harsanyi V
出版信息
Arch Dis Child. 1980 Aug;55(8):641-3. doi: 10.1136/adc.55.8.641.
Abstract
Life-threatening lingual haemorrhage was successfully treated in a 3-year-old haemophiliac who had a high level of inhibitor in his plasma. Repeated plasma exchange with high-dose factor VIII concentrate led to a cessation of bleeding. Immunosuppressive treatment introduced at the time of plasmapheresis and carried out for 6 weeks seems to have prevented the return of the inhibitor.
摘要
一名3岁血浆中抑制剂水平较高的血友病患者的危及生命的舌部出血得到了成功治疗。反复进行高剂量凝血因子VIII浓缩物的血浆置换导致出血停止。在血浆置换时引入并进行6周的免疫抑制治疗似乎防止了抑制剂的再次出现。
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Control of life-threatening bleeding by combined plasmapheresis and immunosuppressive treatment in a haemophiliac with inhibitors.通过血浆置换和免疫抑制治疗联合控制一名患有抑制物的血友病患者的危及生命的出血。
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本文引用的文献
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Immunosuppressive treatment in haemophiliacs with inhibitors to factor VIII and factor IX.对患有VIII因子和IX因子抑制物的血友病患者进行免疫抑制治疗。
Scand J Haematol. 1976 May;16(5):369-82. doi: 10.1111/j.1600-0609.1976.tb00330.x.
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Letter: Prothrombin-complex concentrate in treatment of classical haemophilia with factor-VIII antibody.
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