Jacobsen J B, Neilsen H, Brinkløv M M, Stokke D B, Hartmann-Andersen J F
Br J Anaesth. 1980 Sep;52(9):925-30. doi: 10.1093/bja/52.9.925.
The efficiency of two patient-dependent, variable performance techniques of oxygen therapy in relieving hypoxaemia after upper abdominal surgery was compared. A high-flow system delivered a humidified mixture of oxygen 2 litre min-1 and air 13 litre min-1 through a cannula inserted into the anterior nares. The low-flow system delivered 2 litre min-1 of dry oxygen into the nasopharynx through a catheter. Thirteen otherwise healthy patients received either high-flow oxygen therapy for 30 min followed by low-flow oxygen therapy for a further 30 min after operation or the same therapy in reverse order. With the patients breathing room air, arterial hypoxaemia could be demonstrated with Pao2 inversely related to age. The increase of Pao2 during either oxygen treatment was significantly greater with the low flow system.
比较了两种依赖患者的可变性能氧疗技术在上腹部手术后缓解低氧血症方面的效果。高流量系统通过插入前鼻孔的插管输送每分钟2升氧气和每分钟13升空气的湿化混合气体。低流量系统通过导管将每分钟2升的干燥氧气输送到鼻咽部。13名其他方面健康的患者在术后接受了高流量氧疗30分钟,随后低流量氧疗30分钟,或者以相反顺序接受相同的治疗。当患者呼吸室内空气时,可证明存在动脉低氧血症,动脉血氧分压(Pao2)与年龄呈负相关。在任何一种氧疗过程中,低流量系统使Pao2的升高都显著更大。