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长期肠内高营养对犬胰腺分泌的影响。

Effects of long term enteral hyperalimentation on pancreatic secretion in dogs.

作者信息

Hisano S, Yokota T, Nara M, Nakase A, Tobe T

出版信息

Gastroenterol Jpn. 1980;15(5):500-9. doi: 10.1007/BF02773916.

DOI:10.1007/BF02773916
PMID:6777230
Abstract

Acute and chronic experiments in adult mongrel dogs were performed to investigate the influences of a low residue diet (Group I) and an elemental diet (Group II) on pancreatic function. 1) In the acute experiment, intraduodenal administration of the low residue diet produced a significant increase in amylase output in pancreatic juice, while the elemental diet die not. 2) Intragastric administration of the low residue diet or elemental diet to conscious dogs showed little difference between the two groups regarding secretin and gastrin release, at the same pH. 3) Long term enteral hyperalimentation showed that it is the low residue diets which enhance pancreatic secretions. 4) In both groups, carbohydrate metabolism, liver function and electrolyte balance were satisfactorily maintained during long term enteral hyperalimentation and morphologic changes of the liver, pancreas and small intestine were not evident. 5) From the viewpoint of nutritional management, low residue diets should be prescribed in some cases of alimentary surgery.

摘要

对成年杂种犬进行急性和慢性实验,以研究低渣饮食(第一组)和要素饮食(第二组)对胰腺功能的影响。1)在急性实验中,十二指肠内给予低渣饮食可使胰液中淀粉酶的分泌量显著增加,而要素饮食则无此作用。2)对清醒犬胃内给予低渣饮食或要素饮食,在相同pH值下,两组在促胰液素和胃泌素释放方面差异不大。3)长期肠内高营养显示,是低渣饮食增强了胰腺分泌。4)两组在长期肠内高营养期间,碳水化合物代谢、肝功能和电解质平衡均得到满意维持,肝脏、胰腺和小肠的形态学变化不明显。5)从营养管理的角度来看,在某些消化道手术病例中应采用低渣饮食。

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本文引用的文献

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Physiological determination of release of secretin and pancreozymin from intestine of dogs with transplanted pancreas.移植胰腺犬肠道中促胰液素和缩胆囊素释放的生理学测定
Am J Physiol. 1951 Feb;164(2):527-45. doi: 10.1152/ajplegacy.1951.164.2.527.
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A stable starch substrate for the determination of amylase in serum and other body fluids.一种用于测定血清及其他体液中淀粉酶的稳定淀粉底物。
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Quantitative nutritional studies with water-soluble, chemically defined diets. I. Growth, reproduction and lactation in rats.
水溶性化学限定日粮的定量营养研究。I. 大鼠的生长、繁殖和泌乳
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Influence of glucagon on pancreatic exocrine secretion.胰高血糖素对胰腺外分泌的影响。
Gastroenterology. 1969 Mar;56(3):531-7.
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Factors influencing villus size in the small intestine of adult rats as revealed by transposition of intestinal segments.通过肠段转位揭示的影响成年大鼠小肠绒毛大小的因素
Am J Anat. 1970 Jan;127(1):15-36. doi: 10.1002/aja.1001270104.
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Infusion catheter sepsis: an increasing threat.输液导管败血症:日益严重的威胁。
Ann Surg. 1971 Jan;173(1):148-51. doi: 10.1097/00000658-197101000-00023.
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Localization of cholecystokinin release in intestine of the dog.狗肠道中胆囊收缩素释放的定位
Am J Physiol. 1972 Jan;222(1):16-20. doi: 10.1152/ajplegacy.1972.222.1.16.
8
Use of a chemically defined, liquid, elemental diet for nutritional management of fistulas of the alimentary tract.使用化学组成明确的液态要素膳对消化道瘘进行营养管理。
Am J Surg. 1971 Feb;121(2):174-83. doi: 10.1016/0002-9610(71)90096-1.
9
Intraluminal and postabsorptive effects of amino acids on pancreatic enzyme secretion.氨基酸对胰腺酶分泌的管腔内及吸收后效应。
J Lab Clin Med. 1973 Aug;82(2):241-8.
10
Intrajejunal administration of an elemental diet at neutral pH avoids pancreatic stimulation. Studies in dog and man.在中性pH值下空肠内给予要素饮食可避免胰腺受到刺激。对狗和人的研究。
Am J Surg. 1973 Nov;126(5):606-14. doi: 10.1016/s0002-9610(73)80007-8.