Schiff I, Regestein Q, Schinfeld J, Ryan K J
Maturitas. 1980 Oct;2(3):179-83. doi: 10.1016/0378-5122(80)90002-x.
The effects of conjugated oestrogens 0.625 mg and placebo on adrenal and pituitary hormones were compared in 10 postmenopausal women during their sleep by means of double blind prospective crossover study. On placebo, the women had nocturnal variations in LH, prolactin and cortisol concentrations. However, oestrogen administration selectively blunted LH and prolactin changes, but not the rise in cortisol.
通过双盲前瞻性交叉研究,比较了10名绝经后女性在睡眠期间服用0.625毫克共轭雌激素和安慰剂对肾上腺及垂体激素的影响。服用安慰剂时,这些女性的促黄体生成素(LH)、催乳素和皮质醇浓度存在夜间变化。然而,服用雌激素有选择地减弱了LH和催乳素的变化,但并未减弱皮质醇的升高。