Franssila K O
Ann Chir Gynaecol. 1978;67(2):49-57.
During a five-year period, 1958--62, 97 cases of papillary thyroid carcinoma had been diagnosed in Finland. Twenty two of these patients died from this cancer during a follow-up of 13--18 years. Five of them had initially had distant metastases. Of the remainder seven had had no thyroid operation or only a biopsy, nine an operable tumour that invaded through the thyroid capsule (extrathyroid) and only one a primary tumour confined to the thyroid (intrathyroid). The mortality rates were: 83% for patients with distant metastases, 47% for patients with no thyroid operation, 28% for patients with extrathyroid tumours, and 4% for patients with intrathyroid tumours. Death from an intrathyroid or occult papillary carcinoma that does not show initial distant metastases seems to be exceptional, also if the thyroid operation has been unilateral.
在1958年至1962年的五年期间，芬兰诊断出97例甲状腺乳头状癌。在13至18年的随访中，这些患者中有22人死于这种癌症。其中5人最初有远处转移。其余患者中，7人未进行甲状腺手术或仅做了活检，9人有可手术切除的肿瘤且肿瘤侵犯了甲状腺包膜（甲状腺外），只有1人原发性肿瘤局限于甲状腺（甲状腺内）。死亡率分别为：有远处转移的患者为83%，未进行甲状腺手术的患者为47%，甲状腺外肿瘤患者为28%，甲状腺内肿瘤患者为4%。甲状腺内或隐匿性乳头状癌且无初始远处转移的患者死亡似乎很罕见，即使甲状腺手术是单侧的也是如此。
