Bush M, Montali R J, Kleiman D G, Randolph J, Abramowitz M D, Evans R F
J Am Vet Med Assoc. 1980 Nov 1;177(9):858-62.
Diaphragmatic defects were identified in 11 of 130 golden lion tamarins. Seven of the cases were found at necropsy (52 tamarins) and 4 were diagnosed by radiography (78 tamarins). When screening radiography revealed a thoracic mass, a barium series was indicated and either demonstrated loops of bowel within the thorax or suggested liver displacement by the cranial location of the intestine. In 1 case, pneumoperitoneum aided in the diagnosis, by showing liver displacement cranially in an eventration of the diaphragm. The 4 defects diagnosed clinically were successfully corrected surgically. The defects mainly involved the ventromedial to lateral aspect of the costal and sternal muscular portions of the diaphragms. Either a thin pleuroperitoneal sac remained or wide gaps were associated with herniation of abdominal contents into the thorax. Of the 11 affected tamarins, 10 were closely related and the other had no direct consanguinity. An autosomal recessive mode of inheritance was suggested, but other genetic factors may have been involved.
在130只金狮狨猴中，有11只被发现存在膈肌缺陷。其中7例是在尸检时发现的（共检查了52只狨猴），4例是通过X光检查诊断出来的（共检查了78只狨猴）。当筛查X光显示胸部有肿物时，会进行钡餐造影检查，结果要么显示胸腔内有肠袢，要么提示由于肠管位于胸腔上部导致肝脏移位。有1例，气腹有助于诊断，因为它显示在膈肌膨出时肝脏向上移位。临床上诊断出的4例缺陷均通过手术成功矫正。这些缺陷主要累及膈肌肋部和胸骨部肌肉从腹内侧到外侧的部分。要么残留一个薄的胸膜腹膜囊，要么存在宽大的间隙并伴有腹腔内容物疝入胸腔。在11只受影响的狨猴中，10只是近亲关系，另一只没有直接的血缘关系。提示为常染色体隐性遗传模式，但可能还涉及其他遗传因素。
