Hiemstra S, Ziegler E
MMW Munch Med Wochenschr. 1980 Dec 5;122(49):1777-80.
The effect and tolerance of a single daily tablet of Tenormin 100 in the treatment of essential hypertension was investigated in a private practice multicenter trial. 4083 Patients with mild to moderate essential hypertension (age range 15--89 years) were treated for four weeks. According to WHO criteria 83.4% of all patients were clearly hypertensive. At the end of the treatment 88.8% were under satisfactory control. The treatment was generally well tolerated. No hitherto unknown side effects occurred. The global therapeutic success rating, also taking into account the side effects, was confirmed mathematically and showed a success rate of 82% for Atenolol in this trial.
在一项私人诊所多中心试验中,研究了每日服用一片100毫克天诺敏治疗原发性高血压的疗效和耐受性。4083例轻度至中度原发性高血压患者(年龄范围15 - 89岁)接受了为期四周的治疗。根据世界卫生组织标准,所有患者中83.4%为明显高血压患者。治疗结束时,88.8%的患者血压得到满意控制。该治疗总体耐受性良好。未出现迄今未知的副作用。综合考虑副作用的整体治疗成功评级经数学验证,在该试验中显示阿替洛尔的成功率为82%。