Chanda J J, Callen J P
Arch Dermatol. 1978 Aug;114(8):1197-80. doi: 10.1001/archderm.114.8.1197.
Cutaneous manifestations of histoplasmosis may be divided into primary and secondary lesions. Primary cutaneous histoplasmosis is rare; to our knowledge, there are only three reported cases in the literature. Secondary cutaneous histoplasmosis develops during the course of disseminated disease. An isolated nodule of the hand was the initially appearing sign of recurrent disseminated disease in our patient. Because of the extreme rarity of primary cutaneous histoplasmosis, cutaneous lesions that are proven to be due to histoplasmosis should alert the physician to the presence of disseminated disease.
组织胞浆菌病的皮肤表现可分为原发性和继发性损害。原发性皮肤组织胞浆菌病罕见；据我们所知，文献中仅报道过3例。继发性皮肤组织胞浆菌病在播散性疾病过程中发生。手部孤立性结节是我们患者复发性播散性疾病最初出现的体征。由于原发性皮肤组织胞浆菌病极为罕见，经证实由组织胞浆菌病引起的皮肤损害应提醒医生存在播散性疾病。
