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正常人溶血红细胞中的免疫反应性胰岛素。

Immunoreactive insulin in haemolyzed erythrocytes of normal humans.

作者信息

Matulevicius V, Coculescu M, Urbanavicius V

出版信息

Physiologie. 1980 Jul-Sep;17(3):217-9.

PMID:6779295
Abstract

Immunoreactive insulin level (IRI) in haemolyzed (HE) of normal fasting subjects was 49.2 +/- 3.5 microU/ml. It was approximately 5 times higher compared within the plasma levels of the same subjects. Recovery and dilution tests for insulin in HE were positive. After an intravenous glucose load IRI in HE decreased to 14.3 +/- 3.6 microU/ml with 5 minutes and was low during 1 hour after glucose administration. Authors results suggest the presence of insulin in human erythrocytes and it release from erythrocytes during the first phase after glucose loading.

摘要

正常空腹受试者溶血样本(HE)中的免疫反应性胰岛素水平(IRI)为49.2±3.5微单位/毫升。与同一受试者的血浆水平相比,该水平大约高5倍。对HE中的胰岛素进行回收和稀释试验呈阳性。静脉注射葡萄糖负荷后,HE中的IRI在5分钟内降至14.3±3.6微单位/毫升,并在给予葡萄糖后的1小时内保持较低水平。作者的结果表明人红细胞中存在胰岛素,并且在葡萄糖负荷后的第一阶段胰岛素从红细胞中释放出来。

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