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[高活性物质浓度的丹曲林溶液。初步交流(作者译)]

[Dantrolen solution of high active substance concentration. Preliminary communication (author's transl)].

作者信息

Rommelsheim K, Lauven P, Westhofen P, Stenger I, Stoeckel H

出版信息

Anasth Intensivther Notfallmed. 1980 Oct;15(5):423-7.

PMID:6779658
Abstract

The effectivity of treatment of a dramatically progressing malignant hyperthermia with Dantrolen depends, inter alia, on the easy production and applicability of the preparation. The modification described in this article, of an intravenously injectable Dantrolen solution which contains 10.0 mg active substance in 1.0 ml of a mixture of ethanol, glycerin and water, seems to meet these conditions, as established by experimental investigation.

摘要

用丹曲林治疗急剧进展的恶性高热的有效性,尤其取决于该制剂的易于生产和适用性。本文所述的丹曲林静脉注射溶液的改良制剂,在1.0毫升乙醇、甘油和水的混合液中含有10.0毫克活性物质,经实验研究证实,似乎符合这些条件。

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